[MAT-05]Pickering high internal phase emulsions (HIPEs) templated super-hydrophobic-oleophilic elastic foams for highly efficient oil/water separation

Highly porous and elastic poly (butyl acrylate)-polydimethylsiloxane (PBA-PDMS)-based foams with superhydrophobic and superoleophilic properties, controllable pore structure, adjustable surface and mechanical properties are fabricated by templating water-in-oil (w/o) Pickering high internal phase emulsions. The prepared foam materials display excellent water-repellent, self-cleaning, oil absorbing behavior, and can be recycled and reused directly, making them suitable for highly efficient oil/water separation and industrial water purification.

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[BIO-04]Development of advanced photodynamic molecular beacons with multiple controls for targeted photodynamic therapy

Controlling the photoactivity of photosensitizers via tumor-associated stimuli is a promising approach to overcome the non-specific toxicity of photodynamic therapy. The co-called photodynamic molecular beacons (PMBs) are quenched in the native form, but are activated upon interactions with cancer-related stimuli, resulting in restoration in fluorescence emission and reactive oxygen species generation. Two dual activatable zinc(II) phthalocyanine (ZnPc)-based PMBs are reported in this presentation, which are fully activated in the presence of both glutathione and cathepsin B as demonstrated in a buffered solution and a range of cancer cells. The trimeric ZnPc-based PMB has been further conjugated with a tumor-targeting peptide, of which its photobiological properties are also reported.

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[ANAL-01]Polydopamine patterned perfluorinated surfaces for bead-free digital immunoassays

We developed a bead-free digital ELISA approach using a PDA patterned perfluorinated substrate. By negative microcontact printing with improved resolution, we proposed a robust and simple method to create millions of microdroplets. We were able to capture single target proteins on each PDA spot without microbeads, greatly economizing the total cost of digital ELISA. Our platform achieved a over 270-fold higher sensitivity for human IL-6 detection compared with commercial ELISA kits, showing great potential in digital bioassays.

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